Kanamycin in experimental guinea pig tuberculosis
نویسندگان
چکیده
منابع مشابه
Stimulation of epithelioid cell response in experimental guinea pig tuberculosis.
In the course of experiments on the effects of anti-spleen tissue serum on the rate of wound healing in experimental animals (Maltz et al. 1948a, b), the local histological response observed led us to consider the effect of such sera on pathological processes. Miale (1947) reported that such antisera elicited a mononuclear cell response in the peripheral blood of dogs. This finding supported ou...
متن کاملExperimental syphilis: guinea pig model.
Outbred Hartley male guinea pigs (300-400 g) were infected intradermally with various concentrations of Treponema pallidum Nichols strain in the pubic region. The median lethal dose (ID50) was approximately 10(5). The animals produced lesions visible by darkfield microscopy, treponemal antibodies (IgG only), and histopathological changes in the lymphoid organs. Though less susceptible to T pall...
متن کاملKaryotype of Hairless Guinea pig
Chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. Chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied using metaphase spreads of bone marrows and G banding techniques. The chromosomes diploid number was 2n= 64 and polymorphism of three type chro...
متن کاملExperimental congenital syphilis: guinea pig model.
Neonates born to female guinea pigs of either a highly susceptible (C4D) or a resistant (Albany) strain, infected prior to or during pregnancy with a single dose of Treponema pallidum, showed in their sera from the first day of life immunoglobulin M (IgM) antibodies to T. pallidum, circulating immune complexes consisting of IgM antibodies and treponemal antigens, and IgM rheumatoid factor. Alth...
متن کاملExperimental ocular tuberculosis in guinea pigs.
OBJECTIVE To develop an animal model of intraocular tuberculosis (TB) with features of pulmonary TB and extrapulmonary dissemination to the eye. METHODS Hartley strain guinea pigs were infected via an aerosol route with virulent Mycobacterium tuberculosis. One group of guinea pigs was infected with a relatively low bacterial inoculum and received no treatment. A second group of guinea pigs re...
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ژورنال
عنوان ژورنال: Nippon Saikingaku Zasshi
سال: 1957
ISSN: 1882-4110,0021-4930
DOI: 10.3412/jsb.12.919